Multi-optical-wavelength ultrasound-modulated optical tomography: a phantom study.

Optical Characterization of NIPAM and PAGAT Polymer Gels for Radiation Dosimetry

Introduction The purpose of the current study was to determine optical sensitivity of N-isopropyl acrylamide NIPAM and polyacrylamide gelatin and tetrakis hydroxymethyl phosphoniun chloride (PAGAT) polymer gels for different wavelength of visible light spectrum applied in optical computed tomography method. Materials and Methods NIPAM and PAGAT polymer gels with conventional formulations used f...

Development of a multi-wavelength diffuse optical tomography system for early diagnosis of rheumatoid arthritis: simulation, phantoms and healthy human studies

A multi-wavelength diffuse optical tomography (DOT) system has been developed to directly extract physiological information, such as total haemoglobin concentration, from tissue in human hand joints. Novel methods for 3D surface imaging and spectrally constrained image reconstruction are introduced and their potential application to imaging of rheumatoid arthritis is discussed. Results are pres...

Spectral hole burning for ultrasound-modulated optical tomography of thick tissue.

We apply spectral hole burning (SHB)-aided detection in ultrasound-modulated optical tomography (UOT) to image optical heterogeneities in thick tissue-mimicking phantom samples and chicken breast tissue. The efficiency of SHB is improved by using a Tm(3+):YAG crystal of higher doping concentration (2.0-atomic%) and a double-pass pumping configuration, in which the pump beam is transmitted throu...

Evaluation of Reflection Optical Imaging Characteristics Using Fluorescence with Near Infrared Wavelength at Different Depths of Tissue Equivalent Phantom

Biomechanical properties of soft tissue measurement using Optical Coherence Elastography

Optical Coherence Tomography (OCT) provides images at near histological resolution, which allows for the identification of micron sized morphological tissue structures. Optical coherence elastography (OCE) measures tissue displacement and utilizes the high resolution of OCT to generate high-resolution stiffness maps. In this work, we explored the potential of measuring shear wave propagation us...